PULSE is the most powerful program for electrophysiological clamp experiments. Running under Windows operating systems and MacOS 9 or lower. It has been developed with the help of leading laboratories worldwide to meet the requirements of the scientific community. It provides the optimal solution for acquisition and analysis of pulsed data. PULSE is custom-made for the application with the EPC 9, but any other amplifier also receives a tremendous boost with PULSE, which supports all patch clamp and voltage clamp amplifiers.

PULSE is the virtual front panel of the EPC 9. It provides you with information of the amplifier state and you can control all values by either mouse or keyboard. All EPC 9 settings will be stored with the raw data for easy reconstruction, analysis, and documentation of your experimental procedures. Automatic routines compensate for leak and series resistance transients and help you to perform these tasks faster and more accurate than even the most experienced user.

PULSE removes the expense of purchasing additional hardware: the sampled data is displayed on the highly customizable digital oscilloscope. With the integrated pulse generator it is very simple to create or to edit complex pulse patterns. A pool of such pulse templates can be stored and the templates are available for execution by just pressing one button.

Other devices like perfusion systems or manipulators can also be controlled by the software.

The ‘extensions’ to PULSE provide further functionality:
The software LockIn amplifier, included in PULSE enables you to measure the membrane capacitance of cells.
The optional software extension X-CHART works as a multichannel chart recorder for up to 16 channels and the FURA extension performs ratiometric fluorescence measurements that can be easily synchronized with the electrophysiological data acquired by PULSE.

PULSE includes driver software for EPC 10, EPC 9, EPC 8, EPC 7, and ITC-16, ITC-18, and LIH 1600. The EPC 10 and LIH 1600 are not supported by PULSE on MacOS 9 or lower.

Further programs such as PULSEFIT, PULSETOOLS or TAC can immediately process the data obtained with PULSE. Export functions transfer the data to other programs such as IGOR, or save the date as ASCII files.


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Features:
  • Virtual front panel of the EPC 9
  • Supports EPC 9, EPC 9 Double, and EPC 9 triple
  • All other amplifiers (e.g. EPC 8, EPC 7) in combination with an ITC-16 interface are supported
  • All amplifier settings can be controlled by either mouse or keyboard
  • Two channel (A/D) acquisition
  • Three channels D/A (Trigger, auxiliary stimulation channels)
  • Organization of your experimental data (tree structure)
  • Automatic routines for leak and capacitive transient compensation
  • p/n Leak correction
  • Software Gaussian filter
  • Fit of data traces
  • Filters perform excellent signal conditioning
  • Customizable oscilloscope window
  • Integrated software pulse generator
  • Immediate analysis of the just acquired date
  • Online analysis of different parameters
  • Printout of oscilloscope and online analysis
  • Macro features
  • LockIn amplifier for capacitance measurements

  • see requirements