After more than 20 years of successful manufacturing of the EPC 7 classic patch clamp amplifier, HEKA is pleased to introduce the new EPC 7 PLUS. Following the tradition of the manually controlled EPC 7 patch clamp amplifier, the EPC 7 PLUS has all the features of the EPC 7 classic but it offers many improvements that have been implemented according to the wishes, suggestions and proposals of our customers.

The EPC 7 patch clamp amplifier has withstood the test of time and, to this day, it is reliably used in laboratories and teaching facilities around the globe. The manual controls of the amplifier provide a hands-on environment that is ideal for instruction and stimulates user awareness of proper adjustment of critical parameters (e.g., C-fast, C-slow and RS compensation).

The EPC 7 PLUS is a high quality patch clamp amplifier featuring a range-changing headstage. Two different switchable feedback resistors (50 GOhm, 500 MOhm) in the headstage allow performing single-channel and whole-cell recordings with one headstage. Furthermore, for low-noise high-resolution recordings it is possible to switch to high gain during a whole-cell recording.

• Manual control by use of the knobs and switches on the front panel
• High time resolution and low noise for single-channel and whole-cell recordings
• Whole-cell voltage clamp and current clamp studies
• Recordings from artificial membranes
• Range-changing capabilities of the headstage. Two different feedback resistors: 50 GOhm, 500 MOhm
• Extremely wide bandwidth available from the current monitor signal
• Integrated transient cancellation and series-resistance compensation in voltage and current clamp mode.
• 11 selectable gain ranges from 0.5 to 1000 mV/pA
• 100-130 V AC or 200-260 V AC switchable

• See requirements
  

• Holding potential range is increased from ±200 mV to ±500 mV.
• Pipette offset compensation is increased from ±50 mV to ±200 mV.
• RS compensation and C-Fast cancellation are active in current clamp mode.
• A variable 7-pole Bessel filter with 12 steps (0.1, 0.3, 0.5, 0.7, 1,3, 5, 7, 10, 20, 30 kHz, FULL bandwidth) on the current monitor channel replaces the two 3-pole Bessel filters of the EPC 7
• C-slow compensation has been extended with a third range from 10 to 1000 pF